Rapid-Kinetics and Spectroscopy: Stopped-Flow; Fluorescence, Absorbance, Circular Dichroism, Anisotropy Spectrometry

• 3 or 4 independently controlled syringes and 2 or 3 mixers
• dead time down to 0.25 ms with the microvolume cuvette
• Standard Stopped-Flow configuration for all optical modes : absorbance, fluorescence, circular dichroism, fluorescence anisotropy.
• A range of observation cuvettes
• Optional hardware converts SFM-300/SFM-400 for :
  • Chemical Quench-Flow
  • Optical Quench-Flow & optical delay line (PDF file)
  • Freeze Quench (PDF file)
  • X-ray scattering Stopped-Flow
  • Neutron scattering Stopped-Flow (PDF file)
  • EPR Stopped-Flow
  • Cryo-temperature Stopped-Flow (PDF file)
  • Automatic titration (PDF file)
  • Stopped-flow conductimetry (PDF file)
  • Rapid Mixing Temperature Jump System - mT-Jump
  • Difficult access (PDF file)
  • Microgravity experiments
• Mixing ration from 1:1 to 1:100
• Exact control of flow rate
• User selectable syringe volumes
• compatible with :
  • MOS-200
  • MOS-200/M
  • MOS-450/AF-CD
  • MOS-DA
  • MCS-200
• Supplied with the 32-bits Windows-based Bio-Kine32 & SFit software (NT, 2000, XP and Vista).

Click here to download an SFM-300 & 400 brochure (PDF)

Click here to learn more about the Bio-Logic Stopped Flow technology

• Outstanding signal-to-noise ratio
• For fluorescence, light scattering, absorbance, circular dichroism and fluorescence anisotropy (Includes as standard a unique and very sensitive fluorescence anisotropy measurement mode: the EMFA® method)
• Steady state spectral recordings
• Single wavelength Fast-Kinetics recordings

The modularity of the MOS-450 spectrometer makes it economical : a minimum of components to be rearranged for different modes of detection, and expandable.

The MOS-450 spectrometer comes as two basic configurations :

• MOS-450/AF for absorbance and fluorescence modes. This includes a dual illumination monochromator and single-channel detection.
• MOS-450/AF-CD for absorbance, fluorescence, fluorescence anisotropy and circular dichroism modes. This includes the same hardware as the /AF version, with in addition : polarizing optics, photoelastic modulator and synchronous signal detection.

• 256 or 1024 pixels
• 200 to 1100 nm
• up to 1250 spectral/s
• True 100% duty cycle
• Kinetics and steady-state modes
• Absorbance, transmittance, and photon counting modes

Click here to download an MOS-DA brochure (PDF)

Jasco CD link
For J-600, J-700 and J-800 series

We have designed in collaboration with Jasco a mechanical and optical adaptation between the Bio-Logic series of stopped-flow instruments and the Jasco CD spectrometers.

This creates a very efficient and performing instrument for fast kinectics CD recordings.

Features

• Supports SFM-20, SFM-300, SFM-400 instruments
• CD spectra may be recorded either by setting a standard cuvette in the stopped-flow head or by switching to the spectrometer built-in cuvette holder.
• Precise and reproducible optimization of the light transfer to the stopped-flow cuvette.
• Instant optical switch from the stopped-flow to the spectrometer cuvette without removing or misaligning the stopped-flow instrument.
• Two 90° ports on the stopped-flow for recordings of the fluorescence kinetics.